Ethyl Acetate → HCID 25073712, compound

Participants

Reaction Steps

Yellow powder, 170 mg (48%), mp=152-153° C., Rf: 0.48 (EtOAc), 1H NMR (270 MHz, CDCl3) δ 2.67-2.79 (4H, m, 2×CH2), 3.57 (2H, s, CH2), 3.64 (2H, s, CH2), 3.80 (3H, s, CH3O), 3.81 (3H, s, CH3O), 3.82 (3H, s, CH3O), 3.89 (3H, s, CH3O), 5.61 (1H, br, OH), 6.46 (1H, s, ArH), 6.53 (1H, s, ArH), 6.62 (1H, s, ArH), 7.01 (1H, s, ArH), 13C NMR (67.5 MHz, CDCl3) δ 28.6 (CH2), 50.6 (CH2), 55.3 (CH2), 55.8 (CH2), 56.0 (CH3O), 56.2 (CH3O), 56.6 (CH3O), 56.8 (OCH3), 97.6 (CH(Ar)), 108.9 (CH(Ar)), 114.2 (CH(Ar)), 114.3 (CH(Ar)), 118.0 (C(Ar)), 126.4 (C(Ar)), 127.1 (C(Ar)), 143.1 (C(Ar)), 144.0 (C(Ar)), 144.9 (C(Ar)), 148.5 (C(Ar)) and 152.1 (C(Ar)). LC/MS (APCI−) tr=0.60 min m/z 358.21(M−H)−; MeOH/H2O 95/5; HPLC tr=2.41 min (98.2%). (CH3CN/H2O90/10)

Provenance & Evidence