Ethyl 3-oxovalerate → 2-[4-(2,2-Dimethylpropionyl)benzyl]-3-oxopentanoic acid ethyl ester

HRID 1944301Notes

Reaction equation

HRID 1944301 reaction equation
[CH2:1]([O:3][C:4](=[O:10])[CH2:5][C:6](=[O:9])[CH2:7][CH3:8])[CH3:2].Br[CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C:19](=[O:24])[C:20]([CH3:23])([CH3:22])[CH3:21])=[CH:15][CH:14]=1>>[CH2:1]([O:3][C:4](=[O:10])[CH:5]([CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C:19](=[O:24])[C:20]([CH3:22])([CH3:21])[CH3:23])=[CH:15][CH:14]=1)[C:6](=[O:9])[CH2:7][CH3:8])[CH3:2]

Participants

3

Reactant 2

HCID 78656Ethyl 3-oxovalerateHCID 128310071-[4-(Bromomethyl)phenyl]-2,2-dimethylpropan-1-one

Product 1

HCID 674591252-[4-(2,2-Dimethylpropionyl)benzyl]-3-oxopentanoic acid ethyl ester

Procedure

The title compound was prepared by the method of Preparation 3a using 3-oxo-pentanoic acid ethyl ester and 1-(4-bromomethylphenyl)-2,2-dimethylpropan-1-one.

Sources & evidence

ORD record
ord-0bffe75eb8e14116869c94d771fcf1e2
Source dataset
uspto-grants-2013_03
Patent number
US08394830B2

Reaction notes

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