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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944307Generated: October 30, 2026

Methyl bromoacetate → [8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester

https://huagongshe.com/reaction/1944307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl bromoacetateHCID 60984—
Reactant8-chloro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-oneHCID 67457911—
Product[8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl esterHCID 67459078—

Reaction Steps

The title compound was prepared by the method of Preparation 7a using 8-chloro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-one and bromoacetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394830B2
Source datasetuspto-grants-2013_03
ORD IDord-86bb72cd93874babb10a57b114e22c0d
Source noteuspto-grants-2013_03