HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorodifluoromethane → [8-Chloro-4-difluoromethoxy-2-isopropyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-yloxy]acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorodifluoromethane | HCID 6372 | — |
| Reactant | [8-Chloro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester | HCID 67456771 | — |
| Product | [8-Chloro-4-difluoromethoxy-2-isopropyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-yloxy]acetic acid methyl ester | HCID 67456768 | — |
Reaction Steps
The title compound was prepared by the method of Preparation 10c using [8-chloro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester and chlorodifluoromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394830B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c7d81c5fc1fa49a8b6be64ad4043945e |
| Source note | uspto-grants-2013_03 |