3-Amino-4-fluorophenol → HCID 86642377, compound

HRID 1944344Notes

Reaction equation

HRID 1944344 reaction equation
C(S[C:6](=[O:24])[CH:7]([CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:18](=[O:23])[C:19]([CH3:22])([CH3:21])[CH3:20])=[CH:14][CH:13]=1)[C:8](=[O:10])[CH3:9])(C)(C)C.[NH2:25][C:26]1[CH:27]=[C:28]([OH:33])[CH:29]=[CH:30][C:31]=1[F:32]>>[CH3:22][C:19]([CH3:20])([CH3:21])[C:18]([C:15]1[CH:14]=[CH:13][C:12]([CH2:11][CH:7]([C:8](=[O:10])[CH3:9])[C:6]([NH:25][C:26]2[CH:27]=[C:28]([OH:33])[CH:29]=[CH:30][C:31]=2[F:32])=[O:24])=[CH:17][CH:16]=1)=[O:23]

Participants

3

Reactant 2

HCID 135191803-Amino-4-fluorophenolHCID 86642375HCID 86642375, compound

Product 1

HCID 86642377HCID 86642377, compound

Procedure

The title compound was prepared by the method of Preparation 11b using 2-[4-(2,2-dimethylpropionyl)benzyl]-3-oxothiobutyric acid S-tert-butyl ester and 3-amino-4-fluorophenol.

Sources & evidence

ORD record
ord-67c69eebbbfe441eb9f4926b66c4a115
Source dataset
uspto-grants-2013_03
Patent number
US08394830B2

Reaction notes

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