tert-Butyl bromoacetate → HCID 67456317, compound

HRID 1944357Notes

Reaction equation

HRID 1944357 reaction equation
[Br:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][C:7]2[C:8](=[O:20])[NH:9][C:10]3[C:15]([C:16]=2[CH3:17])=[C:14]([OH:18])[CH:13]=[CH:12][C:11]=3[F:19])=[CH:4][CH:3]=1.[C:23]([O:27][C:28](=[O:31])[CH2:29]Br)([CH3:26])([CH3:25])[CH3:24]>>[C:23]([O:27][C:28](=[O:31])[CH2:29][O:18][C:14]1[CH:13]=[CH:12][C:11]([F:19])=[C:10]2[C:15]=1[C:16]([CH3:17])=[C:7]([CH2:6][C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:22][CH:21]=1)[C:8](=[O:20])[NH:9]2)([CH3:26])([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 67457687HCID 67457687, compound

Product 1

HCID 67456317HCID 67456317, compound

Procedure

The title compound was prepared by the method of Preparation 7a using 3-(4-bromobenzyl)-8-fluoro-5-hydroxy-4-methyl-1H-quinolin-2-one and bromoacetic acid tert-butyl ester.

Sources & evidence

ORD record
ord-1cbbe8daca7d4e269659a45672df24d5
Source dataset
uspto-grants-2013_03
Patent number
US08394830B2

Reaction notes

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