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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944398Generated: November 2, 2026

3-Benzenesulfonylthiophene-2-carbaldehyde → [3-(3-Benzenesulfonylthiophen-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester

https://huagongshe.com/reaction/1944398

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Benzenesulfonylthiophene-2-carbaldehydeHCID 916262—
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Product[3-(3-Benzenesulfonylthiophen-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl esterHCID 67043955—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester and 3-benzenesulfonylthiophene-2-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-6daa581c9c564e8ab446256a83d15f54
Source noteuspto-grants-2013_03