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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944417Generated: November 3, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → {5-Fluoro-2-methyl-3-[3-(pyridine-2-sulfonyl)thiophen-2-ylmethyl]indol-1-yl}acetic acid methyl ester

https://huagongshe.com/reaction/1944417

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant3-(Pyridine-2-sulfonyl)thiophene-2-carbaldehydeHCID 86652188—
Product{5-Fluoro-2-methyl-3-[3-(pyridine-2-sulfonyl)thiophen-2-ylmethyl]indol-1-yl}acetic acid methyl esterHCID 67025766—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using 3-(pyridine-2-sulfonyl)thiophene-2-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-5c55b542ea544563a2baa61365a30b98
Source noteuspto-grants-2013_03