Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → HCID 67045063, compound

HRID 1944420Notes

Reaction equation

HRID 1944420 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:12]([CH:16]=O)=[CH:13][S:14][CH:15]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([F:31])=[CH:28][CH:29]=2)[CH:24]=[C:23]1[CH3:32]>>[CH3:18][O:19][C:20](=[O:33])[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27]([F:31])=[CH:28][CH:29]=2)[C:24]([CH2:16][C:12]2[C:11]([S:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)(=[O:9])=[O:10])=[CH:15][S:14][CH:13]=2)=[C:23]1[CH3:32]

Participants

3

Reactant 2

HCID 58247161Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 86652189HCID 86652189, compound

Product 1

HCID 67045063HCID 67045063, compound

Procedure

The title compound was prepared by the method of Preparation 1c using 4-(4-chloro-benzenesulfonyl)thiophene-3-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Sources & evidence

ORD record
ord-72064e3900f7447dad4b30ae5305fcc3
Source dataset
uspto-grants-2013_03
Patent number
US08394836B2

Reaction notes

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