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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944429Generated: October 31, 2026

N-Methylaniline → {5-Fluoro-2-methyl-3-[2-(methylphenylsulfamoyl)benzyl]indol-1-yl}acetic acid methyl ester

https://huagongshe.com/reaction/1944429

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylanilineHCID 7515—
Reactant[3-(2-Chlorosulfonylbenzyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl esterHCID 86652191—
Product{5-Fluoro-2-methyl-3-[2-(methylphenylsulfamoyl)benzyl]indol-1-yl}acetic acid methyl esterHCID 67044995—

Reaction Steps

The title compound was prepared by the method of Preparation 20c using [3-(2-chlorosulfonylbenzyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester and N-methylaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-5186fcdbef384a1a935dc8f734a83713
Source noteuspto-grants-2013_03