Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-Chlorobenzenesulphonyl chloride | HCID 17909 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Sodium 3-chlorobenzene-1-sulfinate | HCID 23677431 | 7.1% |
Reaction Steps
A solution of 3-chlorobenzenesulfonyl chloride (3.0 g) in dioxane (40 mL) was treated with a mixture of sodium hydrogen carbonate (2.7 g), sodium sulfite (3.6 g) and water (20 mL), and the resulting mixture was stirred at 75° C. for 30 minutes. The mixture was cooled to room temperature and concentrated under reduced pressure. The residue was triturated with ethanol to afford the title compound as a white solid (0.20 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08394836B2 |
|---|
| Source dataset | uspto-grants-2013_03 |
|---|
| ORD ID | ord-f782cba467544f1285cd026dab12967c |
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| Source note | uspto-grants-2013_03 |
|---|
