Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → HCID 67043735, compound

HRID 1944451Notes

Reaction equation

HRID 1944451 reaction equation
[C:1]1([S:7]([C:10]2[C:11]([CH:18]=O)=[N:12][C:13]([S:16][CH3:17])=[N:14][CH:15]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20][O:21][C:22](=[O:35])[CH2:23][N:24]1[C:32]2[C:27](=[CH:28][C:29]([F:33])=[CH:30][CH:31]=2)[CH:26]=[C:25]1[CH3:34]>>[CH3:20][O:21][C:22](=[O:35])[CH2:23][N:24]1[C:32]2[C:27](=[CH:28][C:29]([F:33])=[CH:30][CH:31]=2)[C:26]([CH2:18][C:11]2[C:10]([S:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)(=[O:8])=[O:9])=[CH:15][N:14]=[C:13]([S:16][CH3:17])[N:12]=2)=[C:25]1[CH3:34]

Participants

3

Reactant 2

HCID 58247161Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 86652197HCID 86652197, compound

Product 1

HCID 67043735HCID 67043735, compound

Procedure

The title compound was prepared by the method of Preparation 1c using 5-benzenesulfonyl-2-methylsulfanylpyrimidine-4-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Sources & evidence

ORD record
ord-8bd711618af248e98f03c3cc778530eb
Source dataset
uspto-grants-2013_03
Patent number
US08394836B2

Reaction notes

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