Methyl Bromide → HCID 67044583, compound

Participants

Reaction Steps

A mixture of 2-phenylsulfamoylnicotinic acid methyl ester (1.8 g), acetonitrile (100 mL) and potassium carbonate (1.9 g) was treated with a mixture of methyl bromide (1.5 mL) and acetonitrile (6.0 mL), and the resulting mixture was stirred at room temperature for 24 hours. The mixture was concentrated under reduced pressure, triturated with dichloromethane and filtered. The filtrate was concentrated under reduced pressure to afford the title compound as a tan oil (1.5 g).

Provenance & Evidence