Tetrabutylammonium Fluoride → HCID 67044161, compound

Participants

Reaction Steps

A mixture of 5-[2-(tert-butyl-dimethylsilanyloxymethyl)benzenesulfonyl]pyrimidine (2.1 g) and tetrahydrofuran (2.0 mL) was treated with 1.0 M solution of tetrabutylammonium fluoride in tetrahydrofuran (7.5 mL), and the resulting mixture was stirred at room temperature for 30 minutes. The reaction mixture was diluted with ethyl acetate, washed with saturated aqueous sodium chloride solution and dried over magnesium sulfate. The solvent was removed under reduced pressure to afford the title compound a pale brown solid (0.64 g).

Provenance & Evidence