3-Bromo-5-methylthiophene-2-carbaldehyde → 5-Methyl-3-(pyridine-2-sulfonyl)thiophene-2-carbaldehyde

HRID 1944475Notes

Reaction equation

HRID 1944475 reaction equation
Br[C:2]1[CH:6]=[C:5]([CH3:7])[S:4][C:3]=1[CH:8]=[O:9].[Na+].[N:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[S:17]([O-:19])=[O:18]>>[CH3:7][C:5]1[S:4][C:3]([CH:8]=[O:9])=[C:2]([S:17]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][N:11]=2)(=[O:19])=[O:18])[CH:6]=1

Participants

3

Reactant 2

HCID 8188853-Bromo-5-methylthiophene-2-carbaldehydeHCID 23678794Sodium Pyridine-2-sulfinate

Product 1

HCID 866522055-Methyl-3-(pyridine-2-sulfonyl)thiophene-2-carbaldehyde

Procedure

The title compound was prepared by the method of Preparation 7a using 3-bromo-5-methylthiophene-2-carbaldehyde and pyridine-2-sulfinate sodium salt.

Sources & evidence

ORD record
ord-a0fbf17a2c9045a0908416ccfc1b1399
Source dataset
uspto-grants-2013_03
Patent number
US08394836B2

Reaction notes

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