Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → HCID 67044103, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[S:9]([C:12]1[CH:19]=[CH:18][CH:17]=[CH:16][C:13]=1[CH:14]=O)(=[O:11])=[O:10].[CH3:20][O:21][C:22](=[O:35])[CH2:23][N:24]1[C:32]2[C:27](=[CH:28][C:29]([F:33])=[CH:30][CH:31]=2)[CH:26]=[C:25]1[CH3:34]>>[CH3:20][O:21][C:22](=[O:35])[CH2:23][N:24]1[C:32]2[C:27](=[CH:28][C:29]([F:33])=[CH:30][CH:31]=2)[C:26]([CH2:14][C:13]2[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=2[S:9]([C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])(=[O:11])=[O:10])=[C:25]1[CH3:34]Participants
3
Procedure
The title compound was prepared by the method of Preparation 27c using 2-(2,4-dichlorobenzenesulfonyl)benzaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.
Sources & evidence
- ORD record
- ord-a2a7be893c53496eb1dbb6a6d56f979b
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08394836B2
Reaction notes
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