Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → HCID 67044297, compound

HRID 1944480Notes

Reaction equation

HRID 1944480 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=2[CH:13]=O)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:19][O:20][C:21](=[O:34])[CH2:22][N:23]1[C:31]2[C:26](=[CH:27][C:28]([F:32])=[CH:29][CH:30]=2)[CH:25]=[C:24]1[CH3:33]>>[CH3:19][O:20][C:21](=[O:34])[CH2:22][N:23]1[C:31]2[C:26](=[CH:27][C:28]([F:32])=[CH:29][CH:30]=2)[C:25]([CH2:13][C:12]2[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=2[S:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)(=[O:10])=[O:9])=[C:24]1[CH3:33]

Participants

3

Reactant 2

HCID 58247161Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 86651884HCID 86651884, compound

Product 1

HCID 67044297HCID 67044297, compound

Procedure

The title compound was prepared by the method of Preparation 27c using 2-(4-fluorobenzenesulfonyl)benzaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Sources & evidence

ORD record
ord-da3db1280dbb44a699a51eaa1f60e145
Source dataset
uspto-grants-2013_03
Patent number
US08394836B2

Reaction notes

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