4-Chloro-1,3-thiazole-5-carbaldehyde → 4-(Pyridine-2-sulfonyl)thiazole-5-carbaldehyde

HRID 1944484Notes

Reaction equation

HRID 1944484 reaction equation
Cl[C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH:7]=[O:8].[Na+].[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16]([O-:18])=[O:17]>>[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16]([C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH:7]=[O:8])(=[O:18])=[O:17]

Participants

3

Reactant 2

HCID 145013174-Chloro-1,3-thiazole-5-carbaldehydeHCID 23678794Sodium Pyridine-2-sulfinate

Product 1

HCID 866522094-(Pyridine-2-sulfonyl)thiazole-5-carbaldehyde

Procedure

The title compound was prepared by the method of Preparation 42a using 4-chlorothiazole-5-carbaldehyde and pyridine-2-sulfinate sodium salt.

Sources & evidence

ORD record
ord-689d31502ac64accb7a38011e2cb1b28
Source dataset
uspto-grants-2013_03
Patent number
US08394836B2

Reaction notes

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