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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944485Generated: October 25, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → {5-Fluoro-2-methyl-3-[4-(pyridine-2-sulfonyl)thiazol-5-ylmethyl]indol-1-yl}acetic acid methyl ester

https://huagongshe.com/reaction/1944485

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant4-(Pyridine-2-sulfonyl)thiazole-5-carbaldehydeHCID 86652209—
Product{5-Fluoro-2-methyl-3-[4-(pyridine-2-sulfonyl)thiazol-5-ylmethyl]indol-1-yl}acetic acid methyl esterHCID 67044435—

Reaction Steps

The title compound was prepared by the method of Preparation 42b using 4-(pyridine-2-sulfonyl)thiazole-5-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-d48491ad44934edd989fcfcc98ec45ad
Source noteuspto-grants-2013_03