HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944491Generated: October 31, 2026
(3,4-Dichloroisothiazol-5-yl)methanol → 3,4-Dichloro-1,2-thiazole-5-carbaldehyde
https://huagongshe.com/reaction/1944491
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (3,4-Dichloroisothiazol-5-yl)methanol | HCID 16723166 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3,4-Dichloro-1,2-thiazole-5-carbaldehyde | HCID 86652212 | 57% |
Reaction Steps
A mixture of (3,4-dichloroisothiazol-5-yl)methanol (1.1 g), chloroform (150 mL) and manganese dioxide (4.7 g) was stirred at 40° C. for 20 hours. The mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to afford the title compound as a yellow solid (0.62 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08394836B2 |
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| Source dataset | uspto-grants-2013_03 |
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| ORD ID | ord-9d36426fc4e440b4995a198cfe647ddb |
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| Source note | uspto-grants-2013_03 |
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