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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944493Generated: November 3, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → [3-(4-Benzenesulfonyl-3-chloroisothiazol-5-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester

https://huagongshe.com/reaction/1944493

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant4-Benzenesulfonyl-3-chloroisothiazole-5-carbaldehydeHCID 86652213—
Product[3-(4-Benzenesulfonyl-3-chloroisothiazol-5-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl esterHCID 67044606—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester and 4-benzenesulfonyl-3-chloroisothiazole-5-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-f7e2af2ddbf946ebbd68a6a9cfe5ade9
Source noteuspto-grants-2013_03