Hydrochloric Acid → HCID 69519262, compound

Participants

Reaction Steps

To a solution of N-[4-[5-(1-aminoethyl)-1,3,4-oxadiazol-2-yl]-3-chloro-6-((2-methoxyethyl){[trans-2-methylcyclopropyl]methyl}amino)pyridin-2-yl]-N-methylmethanesulfonamide (0.060 g, 0.102 mmol) in 1 mL CH2Cl2 at 0° C. was added 4M HCl in dioxane (0.038 mL, 0.153 mmol). The reaction was concentrated to afford N-[4-[5-(1-aminoethyl)-1,3,4-oxadiazol-2-yl]-3-chloro-6-((2-methoxyethyl){[trans-2-methylcyclopropyl]methyl}amino)pyridin-2-yl]-N-methylmethanesulfonamide hydrochloride as a yellow foam. LCMS [M+H]+=473 (chlorine pattern).

Provenance & Evidence