Trifluoroacetic acid → HCID 69519759, compound

Participants

Reaction Steps

To a solution of tert-butyl (1R)-1-(5-{3-chloro-6-((2-methoxyethyl) {[trans-2-methylcyclopropyl]methyl}amino)-2-[(methylsulfonyl)(pyridin-2-ylmethyl)amino]pyridin-4-yl}-1,3,4-oxadiazol-2-yl)-1-methyl-2-phenylethylcarbamate in CH2Cl2 (1 ml) was added TFA (0.5 ml) and stirred for 30 minutes at rt. Evaporation of the solvent afforded 0.008 g of N-[4-{5-[(1R)-1-amino-1-methyl-2-phenylethyl]-1,3,4-oxadiazol-2-yl}-3-chloro-6-((2-methoxyethyl) {[trans-2-methylcyclopropyl]methyl}amino)pyridin-2-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide. LCMS [M+H]640.2 Exact mass calculated for C31H38ClN7O4S: 640.2468; measured 640.2484

Provenance & Evidence