HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl morpholine oxide → 4-(4-Benzylphenylamino)-6-chloroquinoline-3-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl morpholine oxide | HCID 82029 | — |
| Reactant | (4-(4-Benzylphenylamino)-6-chloroquinolin-3-yl)methanol | HCID 58525065 | — |
| Catalyst | HCID 178419074 | HCID 178419074 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-Benzylphenylamino)-6-chloroquinoline-3-carbaldehyde | HCID 58525117 | — |
Reaction Steps
To a solution of (4-(4-benzylphenylamino)-6-chloroquinolin-3-yl)methanol (800 mg, 2.1 mmol) in CH2Cl2 (9 mL) was added 4-Methylmorpholine N-oxide (377 mg, 3.2 mmol) and tetrapropylammonium perruthenate at room temperature and stirred for overnight. The reaction mixture was filtered and concentrated. The crude product was used without further purification. MS m/z: 373.28 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394818B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7c318c4fa63743be9c78efaea0ab2c52 |
| Source note | uspto-grants-2013_03 |