HCID 178501247, compound → HCID 178501246, compound

HRID 1944706Notes

Reaction equation

HRID 1944706 reaction equation
NC1C=C(S(N[C@H]2CC[C@H](C(OC)=O)CC2)(=O)=O)C=CC=1Cl.[N+:23]([C:26]1[CH:27]=[C:28]([S:33]([NH:36][C@H:37]2[CH2:42][CH2:41][C@H:40]([C:43]([O:45][CH3:46])=[O:44])[CH2:39][CH2:38]2)(=[O:35])=[O:34])[CH:29]=[CH:30][C:31]=1[CH3:32])([O-])=O>>[NH2:23][C:26]1[CH:27]=[C:28]([S:33]([NH:36][C@H:37]2[CH2:38][CH2:39][C@H:40]([C:43]([O:45][CH3:46])=[O:44])[CH2:41][CH2:42]2)(=[O:35])=[O:34])[CH:29]=[CH:30][C:31]=1[CH3:32]

Participants

3

Reactant 2

HCID 178501247HCID 178501247, compound2×HCID 178501249HCID 178501249, compound

Product 1

HCID 178501246HCID 178501246, compound

Procedure

Methyl trans-4-(3-amino-4-methyl-phenylsulfonamido)cyclohexane-carboxylate was prepared by a method analogous to the method used to prepare Intermediate 10 using methyl trans-4-(3-nitro-4-methyl-phenylsulfonamido)cyclohexane-carboxylate (Intermediate 5) as the starting material. MS MH+ 327.2

Sources & evidence

ORD record
ord-8d3a2de24c744ef4a73e861277602e09
Source dataset
uspto-grants-2013_03
Patent number
US08394858B2

Reaction notes

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