Ethanol → HCID 58292138, compound

Participants

Reaction Steps

tert-Butyl 4-(trifluoromethyl)phenylsulfonylcarbamate was prepared by a method analogous to the method disclosed in Tet. Lett. 2004, 45, 8483-8487. tert-Butyl benzyl(4-(trifluoromethyl)phenylsulfonyl)carbamate (Intermediate 86, 520 mg) was hydrogenated (1 atm H2) over 20 wt % Pd(OH)2 (52 mg) in 1:1:1 methanol:ethanol:ethyl acetate (8 ml) for 16 hours. The reaction was filtered over celite and concentrated to yield the title compound (407 mg). MS M−H 324.3

Provenance & Evidence