Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate → Ethyl 1-allyl-4-hydroxycyclohexanecarboxylate

HRID 1944733Notes

Reaction equation

HRID 1944733 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([CH2:20][CH:21]=[CH2:22])[CH2:11][CH2:10][CH:9]([O:12][Si](C(C)(C)C)(C)C)[CH2:8][CH2:7]1)=[O:5])[CH3:2].OC1CCC(C)(C(OCC)=O)CC1>>[CH2:1]([O:3][C:4]([C:6]1([CH2:20][CH:21]=[CH2:22])[CH2:7][CH2:8][CH:9]([OH:12])[CH2:10][CH2:11]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 58230927Ethyl 4-hydroxy-1-methylcyclohexanecarboxylateHCID 58292019Ethyl 1-allyl-4-(tert-butyldimethylsilyloxy)cyclohexanecarboxylate

Product 1

HCID 67225352Ethyl 1-allyl-4-hydroxycyclohexanecarboxylate

Procedure

1-Allyl-4-hydroxy-cyclohexanecarboxylic acid ethyl ester was prepared by deprotecting Intermediate 98 using a method analogous to the method used to prepare Intermediate 67.

Sources & evidence

ORD record
ord-cd2e0e60189f4086af18bb5bae218061
Source dataset
uspto-grants-2013_03
Patent number
US08394858B2

Reaction notes

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