HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalamide → (E)-Ethyl 4-amino-1-(prop-1-enyl)cyclohexane carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalamide | HCID 6956 | — |
| Reactant | (R)-4-Amino-N-(1-(4-fluorophenyl)ethyl)-1-methylcyclohexanecarboxamide | HCID 58292165 | — |
| Reactant | 4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-1-((E)-propenyl)-cyclohexanecarboxylic acid ethyl ester | HCID 67223907 | — |
| Product | (E)-Ethyl 4-amino-1-(prop-1-enyl)cyclohexane carboxylate | HCID 58291990 | — |
Reaction Steps
Intermediate 117 was prepared from Intermediate 116 using standard phthalamide deprotection conditions analogous to the conditions used to prepare Intermediate 77.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394858B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-492ae58e9234494fb85f44412f3131fa |
| Source note | uspto-grants-2013_03 |