HCID 67224098, 화합물 → N-(4-Amino-4-cyanocyclohexyl)-4-trifluoromethyl benzenesulfonamide

HRID 1944741노트

반응식

HRID 1944741 반응식
[NH2:1][C:2]1([C:22]#[N:23])[CH2:7][CH2:6][CH:5]([NH:8][S:9](C2C=CC(OCC)=C(C)C=2)(=[O:11])=[O:10])[CH2:4][CH2:3]1.[F:24][C:25]([F:44])([F:43])[C:26]1[CH:31]=[CH:30][C:29](S(NC2CCC(=O)CC2)(=O)=O)=[CH:28][CH:27]=1>>[NH2:1][C:2]1([C:22]#[N:23])[CH2:3][CH2:4][CH:5]([NH:8][S:9]([C:29]2[CH:30]=[CH:31][C:26]([C:25]([F:44])([F:43])[F:24])=[CH:27][CH:28]=2)(=[O:11])=[O:10])[CH2:6][CH2:7]1

참가 물질

3

반응물 2

HCID 67224098HCID 67224098, 화합물HCID 67224437HCID 67224437, 화합물2회

생성물 1

HCID 67224528N-(4-Amino-4-cyanocyclohexyl)-4-trifluoromethyl benzenesulfonamide

실험 절차

Intermediate 125 was prepared by a method analogous to the method of preparing Intermediate 124 using 4-(trifluoromethyl)-N-(4-oxocyclohexyl)benzenesulfonamide (Intermediate 123) as the starting material.

출처 및 근거

ORD 기록
ord-ebabd7d501dd4bf79eff937480a8c247
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08394858B2

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