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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944746Generated: October 25, 2026

4-(Trifluoromethyl)benzenesulfonamide → Methyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylate

https://huagongshe.com/reaction/1944746

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzenesulfonamideHCID 70018—
ReactantMethyl 4-aminoadamantane-1-carboxylateHCID 57425932—
ReactantHCID 178501250HCID 178501250—
ProductMethyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylateHCID 67225441—

Reaction Steps

Methyl 4-(4-(trifluoromethyl)phenylsulfonamido)-adamantane-1-carboxylate was prepared from 4-amino-adamantane-1-carboxylic acid methyl ester and 4-trifluoromethylbenzene sulfonamide using a method analogous to the method used to prepare Intermediate 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394858B2
Source datasetuspto-grants-2013_03
ORD IDord-7884624e50b84549be58eff509fd4814
Source noteuspto-grants-2013_03