HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenepropanoic acid → Benzenepropanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenepropanoic acid | HCID 107 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzenepropanoyl chloride | HCID 64801 | — |
Reaction Steps
Thionyl chloride (21.8 mL, 300 mmol) was added to a solution of 3-phenylpropionic acid (15 g, 99.9 mol) in DCM (40 mL) and was stirred overnight. The mixture was concentrated in vacuo to yield intermediate (7a), which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394846B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-192ab20c2342429299e16e7823829985 |
| Source note | uspto-grants-2013_03 |