HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-5-(2-Azido-1-hydroxyethyl)-8-(benzyloxy)quinolin-2(1H)-one → (R)-5-(2-Amino-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-5-(2-Azido-1-hydroxyethyl)-8-(benzyloxy)quinolin-2(1H)-one | HCID 58505170 | — |
| Reactant | (R)-5-(2-Amino-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-hydroxyquinolin-2(1H)-one | HCID 59023604 | — |
| Product | (R)-5-(2-Amino-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one | HCID 24996153 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 2, using Intermediate 5 as a substrate. ES/MS calcd. for C11H13N2O3+ 221.1. Found m/z=221.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-3f5f4844f973474b8e1a57f168c3bd26 |
| Source note | uspto-grants-2013_03 |