HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-1-[3-Amino-4-(benzyloxy)phenyl]-2-bromoethanol → (R)-1-(3-Amino-4-(benzyloxy)phenyl)-2-azidoethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-1-[3-Amino-4-(benzyloxy)phenyl]-2-bromoethanol | HCID 11232489 | — |
| Reactant | (R)-5-(2-Azido-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-(benzyloxy)quinolin-2(1H)-one | HCID 58505233 | — |
| Product | (R)-1-(3-Amino-4-(benzyloxy)phenyl)-2-azidoethanol | HCID 57516929 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 1, using Intermediate 14 in place of (R)-8-(benzyloxy)-5-[2-bromo-1-[(tert-butyldimethylsily)oxy]ethyl]quinolin-2(1H)-one. ES/MS calcd. for C15H17N4O2+ 285.1. Found m/z=285 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-46cd3ee1d39f406fa99187b648486070 |
| Source note | uspto-grants-2013_03 |