Benzyl 4-(6-((tert-butyldimethylsily)oxy)hexyl)piperazine-1-carboxylate → 1-(6-((Tert-butyldimethylsilyl)oxy)hexyl)piperazine

HRID 1944860Notes

Reaction equation

HRID 1944860 reaction equation
[Si](OCCCCCCOC1CCNCC1)(C(C)(C)C)(C)C.[Si:22]([O:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][N:36]1[CH2:41][CH2:40][N:39](C(OCC2C=CC=CC=2)=O)[CH2:38][CH2:37]1)([C:25]([CH3:28])([CH3:27])[CH3:26])([CH3:24])[CH3:23]>>[Si:22]([O:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][N:36]1[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]1)([C:25]([CH3:28])([CH3:26])[CH3:27])([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 58505092Benzyl 4-(6-((tert-butyldimethylsily)oxy)hexyl)piperazine-1-carboxylateHCID 58505168HCID 58505168, compound

Product 1

HCID 575169311-(6-((Tert-butyldimethylsilyl)oxy)hexyl)piperazine

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 23, using Intermediate 24 as a substrate. ES/MS calcd. for C16H37N2OSi+ 301.3. Found m/z=301.3 (M+H)+.

Sources & evidence

ORD record
ord-e7fdf02feb6240da834de1f622021b0c
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

Loading…