2,2,2-trifluoro-N-(4-iodo-3-methylphenyl)acetamide → HCID 86659089, compound

HRID 1944869Notes

Reaction equation

HRID 1944869 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]([N:5]([C:7]1[CH:12]=[CH:11][C:10]([C:13]#[C:14][CH2:15][CH2:16][CH2:17][OH:18])=[CH:9][CH:8]=1)C)=[O:4].F[C:22](F)(F)C(NC1C=CC(I)=C(C)C=1)=O>>[F:20][C:2]([F:1])([F:19])[C:3]([NH:5][C:7]1[CH:8]=[CH:9][C:10]([C:13]#[C:14][CH2:15][CH2:16][CH2:17][OH:18])=[C:11]([CH3:22])[CH:12]=1)=[O:4]

Participants

3

Reactant 2

HCID 7137692,2,2-trifluoro-N-(4-iodo-3-methylphenyl)acetamideHCID 57516936HCID 57516936, compound

Product 1

HCID 86659089HCID 86659089, compound

Procedure

The title compound was synthesized in a manner analogous to that described in Intermediate 36, using Intermediate 35 in place of Intermediate 33. ES/MS calcd. for C14H14F3NO2 285.1. Found m/z=286 (M+H)+.

Sources & evidence

ORD record
ord-f3090de663b144ea90b5eee2d1fcfafa
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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