4-(3-Hydroxypropyl)Benzeneboronic Acid → HCID 66988508, compound

HRID 1944892Notes

Reaction equation

HRID 1944892 reaction equation
OCC1C=CC([C:9]2[CH:14]=[CH:13][C:12]([S:15]([C:18]3[CH:19]=[C:20]4[C:25](=[C:26]([CH3:28])[CH:27]=3)[N:24]=[CH:23][C:22]([C:29]([NH2:31])=[O:30])=[C:21]4[NH:32][C:33]3[CH:38]=[CH:37][CH:36]=[C:35]([O:39][CH3:40])[CH:34]=3)(=[O:17])=[O:16])=[CH:11][CH:10]=2)=CC=1.[OH:41][CH2:42][CH2:43][CH2:44][C:45]1[CH:50]=[CH:49][C:48](B(O)O)=[CH:47][CH:46]=1>>[OH:41][CH2:42][CH2:43][CH2:44][C:45]1[CH:50]=[CH:49][C:48]([C:9]2[CH:14]=[CH:13][C:12]([S:15]([C:18]3[CH:19]=[C:20]4[C:25](=[C:26]([CH3:28])[CH:27]=3)[N:24]=[CH:23][C:22]([C:29]([NH2:31])=[O:30])=[C:21]4[NH:32][C:33]3[CH:38]=[CH:37][CH:36]=[C:35]([O:39][CH3:40])[CH:34]=3)(=[O:16])=[O:17])=[CH:11][CH:10]=2)=[CH:47][CH:46]=1

Participants

3

Reactant 2

HCID 51513424-(3-Hydroxypropyl)Benzeneboronic AcidHCID 66988803HCID 66988803, compound

Product 1

HCID 66988508HCID 66988508, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 65, using 4-(3-hydroxypropyl)phenylboronic acid in place of 4-(hydroxymethyl)phenylboronic acid. ES/MS calcd. for C33H32N3O5S+ 582.2. Found m/z=582.3 (M+H)+.

Sources & evidence

ORD record
ord-d508f72b230842db8f76e012189ea316
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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