4-(3-Hydroxypropyl)Benzeneboronic Acid → HCID 66988475, compound

HRID 1944893Notes

Reaction equation

HRID 1944893 reaction equation
OC[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15]([C:18]3[CH:19]=[C:20]4[C:25](=[C:26]([CH3:28])[CH:27]=3)[N:24]=[CH:23][C:22]([C:29]([NH2:31])=[O:30])=[C:21]4[NH:32][C:33]3[CH:38]=[CH:37][CH:36]=[C:35]([O:39][CH3:40])[CH:34]=3)(=[O:17])=[O:16])[CH:10]=2)=[CH:5][CH:4]=1.[OH:41][CH2:42][CH2:43][CH2:44]C1C=CC(B(O)O)=CC=1>>[OH:41][CH2:42][CH2:43][CH2:44][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15]([C:18]3[CH:19]=[C:20]4[C:25](=[C:26]([CH3:28])[CH:27]=3)[N:24]=[CH:23][C:22]([C:29]([NH2:31])=[O:30])=[C:21]4[NH:32][C:33]3[CH:38]=[CH:37][CH:36]=[C:35]([O:39][CH3:40])[CH:34]=3)(=[O:16])=[O:17])[CH:10]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 51513424-(3-Hydroxypropyl)Benzeneboronic AcidHCID 66988923HCID 66988923, compound

Product 1

HCID 66988475HCID 66988475, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 64, using 4-(3-hydroxypropyl)phenylboronic acid in place of 4-(hydroxymethyl)phenylboronic acid. ES/MS calcd. for C33H32N3O5S+ 582.2. Found m/z=582.3 (M+H)+.

Sources & evidence

ORD record
ord-92f3c6f7bc804952b0eec2422b1f5200
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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