HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]pentan-1-ol → 6-((4'-(5-Hydroxypentyl)-(1,1'-biphenyl]-4-yl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]pentan-1-ol | HCID 57516948 | — |
| Reactant | HCID 66988803 | HCID 66988803 | — |
| Product | 6-((4'-(5-Hydroxypentyl)-(1,1'-biphenyl]-4-yl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 66988945 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 65, using 3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]pentan-1-ol in place of 4-(hydroxymethyl)phenylboronic acid. ES/MS calcd. for C35H36N3O5S+ 610.2. Found m/z=610.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-d3871e7b39264da78153106179ea2993 |
| Source note | uspto-grants-2013_03 |