HCID 15515315, compound → HCID 58505075, compound

HRID 1944897Notes

Reaction equation

HRID 1944897 reaction equation
OCC[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].NC1C=CC([C:52]#[C:53][CH2:54][CH2:55][CH2:56][OH:57])=CC=1>>[OH:57][CH2:56][CH2:55][CH2:54][C:53]#[C:52][C:6]1[CH:5]=[CH:4][C:9]([NH:10][C:11]([C:13]2[CH:14]=[C:15]([S:19]([C:22]3[CH:23]=[C:24]4[C:29](=[C:30]([CH3:32])[CH:31]=3)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]4[NH:36][C:37]3[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=3)(=[O:20])=[O:21])[CH:16]=[CH:17][CH:18]=2)=[O:12])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 15515315HCID 15515315, compoundHCID 669880286-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide

Product 1

HCID 58505075HCID 58505075, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 31 in place of 8-aminooctanol. ES/MS calcd. for C36H33N4O6S+ 649.2. Found m/z=649.3 (M+H)+.

Sources & evidence

ORD record
ord-f98a3662362148f2911fb4be758d5565
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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