HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(3-Aminophenyl)pent-4-yn-1-ol → 6-((3-((3-(5-Hydroxypent-1-yn-1-yl)phenyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(3-Aminophenyl)pent-4-yn-1-ol | HCID 57516943 | — |
| Reactant | 6-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide | HCID 66988028 | — |
| Product | 6-((3-((3-(5-Hydroxypent-1-yn-1-yl)phenyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 66988354 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 47 in place of 8-aminooctanol. ES/MS calcd. for C36H33N4O6S+ 649.2. Found m/z=649.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-53c366abeffa4e37a8e6f483733fc962 |
| Source note | uspto-grants-2013_03 |