6-(Methylamino)hexan-1-ol → HCID 66988379, compound

HRID 1944901Notes

Reaction equation

HRID 1944901 reaction equation
OCCCCCCC[CH2:9][NH:10][C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].CN[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][OH:53]>>[OH:53][CH2:52][CH2:51][CH2:50][CH2:49][CH2:48][CH2:47][N:10]([CH3:9])[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:20])=[O:21])[CH:16]=[CH:17][CH:18]=1)=[O:12]

Participants

3

Reactant 2

HCID 109424576-(Methylamino)hexan-1-olHCID 669880286-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide

Product 1

HCID 66988379HCID 66988379, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 21 in place of 8-aminooctanol. ES/MS calcd. for C32H37N4O6S+ 605.2. Found m/z=605 (M+H)+.

Sources & evidence

ORD record
ord-e4bb04a78a074fbd9983d492516aba7c
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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