4-(4-AMINOPHENYL)BENZYL ALCOHOL → HCID 66989066, compound

HRID 1944902Notes

Reaction equation

HRID 1944902 reaction equation
OCCCCCCCCN[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].[NH2:45][C:46]1[CH:51]=[CH:50][C:49]([C:52]2[CH:57]=[CH:56][C:55]([CH2:58][OH:59])=[CH:54][CH:53]=2)=[CH:48][CH:47]=1>>[OH:59][CH2:58][C:55]1[CH:56]=[CH:57][C:52]([C:49]2[CH:48]=[CH:47][C:46]([NH:45][C:11]([C:13]3[CH:14]=[C:15]([S:19]([C:22]4[CH:23]=[C:24]5[C:29](=[C:30]([CH3:32])[CH:31]=4)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]5[NH:36][C:37]4[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=4)(=[O:20])=[O:21])[CH:16]=[CH:17][CH:18]=3)=[O:12])=[CH:51][CH:50]=2)=[CH:53][CH:54]=1

Participants

3

Reactant 2

HCID 13936354-(4-AMINOPHENYL)BENZYL ALCOHOLHCID 669880286-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide

Product 1

HCID 66989066HCID 66989066, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using (4′-amino-[1,1′-biphenyl]-4-yl)methanol in place of 8-aminooctanol. ES/MS calcd. for C38H33N4O6S+ 673.2. Found m/z=673.2 (M+H)+.

Sources & evidence

ORD record
ord-8865a4e0d8ba4d8c97b5af5c488dba20
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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