HCID 58505168, compound → HCID 66988582, compound

HRID 1944904Notes

Reaction equation

HRID 1944904 reaction equation
OCCCCCCCCN[C:11]([C:13]1[CH:14]=[C:15]([S:19]([C:22]2[CH:23]=[C:24]3[C:29](=[C:30]([CH3:32])[CH:31]=2)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]3[NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=2)(=[O:21])=[O:20])[CH:16]=[CH:17][CH:18]=1)=[O:12].[Si:45]([O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][O:59][CH:60]1[CH2:65][CH2:64][NH:63][CH2:62][CH2:61]1)([C:48]([CH3:51])([CH3:50])[CH3:49])([CH3:47])[CH3:46]>>[Si:45]([O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][O:59][CH:60]1[CH2:65][CH2:64][N:63]([C:11]([C:13]2[CH:14]=[C:15]([S:19]([C:22]3[CH:23]=[C:24]4[C:29](=[C:30]([CH3:32])[CH:31]=3)[N:28]=[CH:27][C:26]([C:33]([NH2:35])=[O:34])=[C:25]4[NH:36][C:37]3[CH:42]=[CH:41][CH:40]=[C:39]([O:43][CH3:44])[CH:38]=3)(=[O:20])=[O:21])[CH:16]=[CH:17][CH:18]=2)=[O:12])[CH2:62][CH2:61]1)([C:48]([CH3:51])([CH3:50])[CH3:49])([CH3:47])[CH3:46]

Participants

3

Reactant 2

HCID 58505168HCID 58505168, compoundHCID 669880286-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide

Product 1

HCID 66988582HCID 66988582, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 23 in place of 8-aminooctanol. ES/MS calcd. for C42H57N4O7SSi+ 789.4. Found m/z=789.3 (M+H)+.

Sources & evidence

ORD record
ord-fa148014d0f94b6d93deff4917912f58
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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