(R)-5-(2-Azido-1-hydroxyethyl)-8-(benzyloxy)quinolin-2(1H)-one → HCID 66988062, compound

HRID 1944909Notes

Reaction equation

HRID 1944909 reaction equation
N(C[C@@H](C1C=CC(OCC2C=CC=CC=2)=C2C=1C=CC(=O)N2)O)=[N+]=[N-].[Si]([O:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][N:40]1[CH2:45][CH2:44][N:43]([C:46]([C:48]2[CH:49]=[C:50]([S:54]([C:57]3[CH:58]=[C:59]4[C:64](=[C:65]([CH3:67])[CH:66]=3)[N:63]=[CH:62][C:61]([C:68]([NH2:70])=[O:69])=[C:60]4[NH:71][C:72]3[CH:77]=[CH:76][CH:75]=[C:74]([O:78][CH3:79])[CH:73]=3)(=[O:56])=[O:55])[CH:51]=[CH:52][CH:53]=2)=[O:47])[CH2:42][CH2:41]1)(C(C)(C)C)(C)C>>[OH:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][N:40]1[CH2:41][CH2:42][N:43]([C:46]([C:48]2[CH:49]=[C:50]([S:54]([C:57]3[CH:58]=[C:59]4[C:64](=[C:65]([CH3:67])[CH:66]=3)[N:63]=[CH:62][C:61]([C:68]([NH2:70])=[O:69])=[C:60]4[NH:71][C:72]3[CH:77]=[CH:76][CH:75]=[C:74]([O:78][CH3:79])[CH:73]=3)(=[O:56])=[O:55])[CH:51]=[CH:52][CH:53]=2)=[O:47])[CH2:44][CH2:45]1

Participants

3

Reactant 2

HCID 58505170(R)-5-(2-Azido-1-hydroxyethyl)-8-(benzyloxy)quinolin-2(1H)-oneHCID 66988288HCID 66988288, compound

Product 1

HCID 66988062HCID 66988062, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 5, using Intermediate 85 as a substrate. ES/MS calcd. for C35H42N5O6S+ 660.3. Found m/z=660.3 (M+H)+.

Sources & evidence

ORD record
ord-daa0afe350214c97aa6a2d3bc9f9a80d
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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