HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[[3-[[4-(2-Aminoethyl)phenyl]carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide → 6-((3-((2-(4-(2-Aminoethyl)phenoxy)ethyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[[3-[[4-(2-Aminoethyl)phenyl]carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide | HCID 58505073 | — |
| Reactant | tert-butyl 4-(2-(3-((3-carbamoyl-4-((3-methoxyphenyl)amino)-8-methylquinolin-6-yl)sulfonyl)-N-methylbenzamido)ethoxy)phenethylcarbamate | HCID 66987981 | — |
| Product | 6-((3-((2-(4-(2-Aminoethyl)phenoxy)ethyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 66988306 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 94, using Intermediate 83 as a substrate. ES/MS calcd for C36H38N5O6S+ 668.25. Found m/z=668.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-826b9a8ca6d14140a9f3cc36430f8d57 |
| Source note | uspto-grants-2013_03 |