HCID 66988379, compound → HCID 86659092, compound

HRID 1944930Notes

Reaction equation

HRID 1944930 reaction equation
COC1C=C(NC2C3C(=C(C)C=C(S(C4C=CC=C(C(=O)NCCCCCCCC=O)C=4)(=O)=O)C=3)N=CC=2C(N)=O)C=CC=1.[OH:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][N:52]([CH3:87])[C:53]([C:55]1[CH:56]=[C:57]([S:61]([C:64]2[CH:65]=[C:66]3[C:71](=[C:72]([CH3:74])[CH:73]=2)[N:70]=[CH:69][C:68]([C:75]([NH2:77])=[O:76])=[C:67]3[NH:78][C:79]2[CH:84]=[CH:83][CH:82]=[C:81]([O:85][CH3:86])[CH:80]=2)(=[O:63])=[O:62])[CH:58]=[CH:59][CH:60]=1)=[O:54]>>[CH3:86][O:85][C:81]1[CH:80]=[C:79]([NH:78][C:67]2[C:66]3[C:71](=[C:72]([CH3:74])[CH:73]=[C:64]([S:61]([C:57]4[CH:58]=[CH:59][CH:60]=[C:55]([C:53](=[O:54])[N:52]([CH3:87])[CH2:51][CH2:50][CH2:49][CH2:48][CH2:47][CH:46]=[O:45])[CH:56]=4)(=[O:63])=[O:62])[CH:65]=3)[N:70]=[CH:69][C:68]=2[C:75]([NH2:77])=[O:76])[CH:84]=[CH:83][CH:82]=1

Participants

3

Reactant 2

HCID 66988379HCID 66988379, compoundHCID 866590914-[(3-Methoxyphenyl)amino]-8-methyl-6-[[3-[(8-oxooctyl)carbamoyl]phenyl]sulfonyl]quinoline-3-carboxamide

Product 1

HCID 86659092HCID 86659092, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 112, using Intermediate 80 as a substrate. ES/MS calcd. for C32H35N4O6S+ 603.2. Found m/z=603 (M+H)+.

Sources & evidence

ORD record
ord-7bec67e346024ac58b1aebe3acb84981
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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