HCID 66988230, compound → HCID 86659093, compound

HRID 1944931Notes

Reaction equation

HRID 1944931 reaction equation
COC1C=C(NC2C3C(=C(C)C=C(S(C4C=CC=C(C(=O)NCCCCCCCC=O)C=4)(=O)=O)C=3)N=CC=2C(N)=O)C=CC=1.[OH:45][CH2:46][CH2:47][CH2:48][C:49]#[C:50][C:51]1[CH:56]=[CH:55][C:54]([NH:57][C:58]([C:60]2[CH:61]=[C:62]([S:66]([C:69]3[CH:70]=[C:71]4[C:76](=[C:77]([CH3:79])[CH:78]=3)[N:75]=[CH:74][C:73]([C:80]([NH2:82])=[O:81])=[C:72]4[NH:83][C:84]3[CH:89]=[CH:88][CH:87]=[C:86]([O:90][CH3:91])[CH:85]=3)(=[O:68])=[O:67])[CH:63]=[CH:64][CH:65]=2)=[O:59])=[CH:53][C:52]=1[CH3:92]>>[CH3:91][O:90][C:86]1[CH:85]=[C:84]([NH:83][C:72]2[C:71]3[C:76](=[C:77]([CH3:79])[CH:78]=[C:69]([S:66]([C:62]4[CH:63]=[CH:64][CH:65]=[C:60]([C:58](=[O:59])[NH:57][C:54]5[CH:55]=[CH:56][C:51]([C:50]#[C:49][CH2:48][CH2:47][CH:46]=[O:45])=[C:52]([CH3:92])[CH:53]=5)[CH:61]=4)(=[O:68])=[O:67])[CH:70]=3)[N:75]=[CH:74][C:73]=2[C:80]([NH2:82])=[O:81])[CH:89]=[CH:88][CH:87]=1

Participants

3

Reactant 2

HCID 66988230HCID 66988230, compoundHCID 866590914-[(3-Methoxyphenyl)amino]-8-methyl-6-[[3-[(8-oxooctyl)carbamoyl]phenyl]sulfonyl]quinoline-3-carboxamide

Product 1

HCID 86659093HCID 86659093, compound

Procedure

The title compound was synthesized in a manner analogous to that described in Intermediate 112, using Intermediate 75 as a substrate. ES/MS calcd. for C37H32N4O6S 660.2. Found m/z=661 (M+H)+.

Sources & evidence

ORD record
ord-50d3332ec3f842589f58cd5a3154ad5a
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

Loading…