HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-((3-((4'-(4-Hydroxybutyl)-[1,1'-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide → 4-((3-Methoxyphenyl)amino)-8-methyl-6-((3-((4'-(4-oxobutyl)-(1,1-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)quinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-((3-((4'-(4-Hydroxybutyl)-[1,1'-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 66988346 | — |
| Reactant | 4-[(3-Methoxyphenyl)amino]-8-methyl-6-[[3-[(8-oxooctyl)carbamoyl]phenyl]sulfonyl]quinoline-3-carboxamide | HCID 86659091 | — |
| Product | 4-((3-Methoxyphenyl)amino)-8-methyl-6-((3-((4'-(4-oxobutyl)-(1,1-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)quinoline-3-carboxamide | HCID 86659098 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 112, using IBX in place of Dess-Martin reagent and Intermediate 90 as a substrate. ES/MS calcd. for C41H37N4O6S+ 713.2. Found m/z=713.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-93c0d59e4f174be199b04c0723b39883 |
| Source note | uspto-grants-2013_03 |