HCID 66988923, compound → HCID 86659101, compound

HRID 1944939Notes

Reaction equation

HRID 1944939 reaction equation
COC1C=C(NC2C3C(=C(C)C=C(S(C4C=CC=C(C(=O)NCCCCCCCC=O)C=4)(=O)=O)C=3)N=CC=2C(N)=O)C=CC=1.[OH:45][CH2:46][C:47]1[CH:52]=[CH:51][C:50]([C:53]2[CH:58]=[CH:57][CH:56]=[C:55]([S:59]([C:62]3[CH:63]=[C:64]4[C:69](=[C:70]([CH3:72])[CH:71]=3)[N:68]=[CH:67][C:66]([C:73]([NH2:75])=[O:74])=[C:65]4[NH:76][C:77]3[CH:82]=[CH:81][CH:80]=[C:79]([O:83][CH3:84])[CH:78]=3)(=[O:61])=[O:60])[CH:54]=2)=[CH:49][CH:48]=1>>[CH:46]([C:47]1[CH:52]=[CH:51][C:50]([C:53]2[CH:58]=[CH:57][CH:56]=[C:55]([S:59]([C:62]3[CH:63]=[C:64]4[C:69](=[C:70]([CH3:72])[CH:71]=3)[N:68]=[CH:67][C:66]([C:73]([NH2:75])=[O:74])=[C:65]4[NH:76][C:77]3[CH:82]=[CH:81][CH:80]=[C:79]([O:83][CH3:84])[CH:78]=3)(=[O:60])=[O:61])[CH:54]=2)=[CH:49][CH:48]=1)=[O:45]

Participants

3

Reactant 2

HCID 66988923HCID 66988923, compoundHCID 866590914-[(3-Methoxyphenyl)amino]-8-methyl-6-[[3-[(8-oxooctyl)carbamoyl]phenyl]sulfonyl]quinoline-3-carboxamide

Product 1

HCID 86659101HCID 86659101, compound

Procedure

The title compound was synthesized in a manner analogous to that described for Intermediate 112, using Intermediate 64 as a substrate. ES/MS calcd. for C31H26N3O5S+ 552.2. Found m/z=552.3 (M+H)+.

Sources & evidence

ORD record
ord-7743b10e03da403c9bc6fa785985ed37
Source dataset
uspto-grants-2013_03
Patent number
US08394829B2

Reaction notes

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