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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944944Generated: October 30, 2026

6-((4'-(5-Hydroxypentyl)-(1,1'-biphenyl]-3-yl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide → 4-((3-Methoxyphenyl)amino)-8-methyl-6-((4'-(5-oxopentyl)-[1,1'-biphenyl]-3-yl)sulfonyl)quinoline-3-carboxamide

https://huagongshe.com/reaction/1944944

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-((4'-(5-Hydroxypentyl)-(1,1'-biphenyl]-3-yl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamideHCID 66988398—
Reactant4-((3-Methoxyphenyl)amino)-8-methyl-6-((3-((4'-(4-oxobutyl)-(1,1-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)quinoline-3-carboxamideHCID 86659098—
Product4-((3-Methoxyphenyl)amino)-8-methyl-6-((4'-(5-oxopentyl)-[1,1'-biphenyl]-3-yl)sulfonyl)quinoline-3-carboxamideHCID 86659106—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 124, using Intermediate 69 as a substrate. ES/MS calcd. for C35H34N3O5S+ 608.2. Found m/z=608.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394829B2
Source datasetuspto-grants-2013_03
ORD IDord-41af432f926b46428f7b46df88ab2f94
Source noteuspto-grants-2013_03